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Friday, July 07, 2017

Insulin is an anabolic hormone, that is, it increases the storage of glucose, fatty acids and amino acids in cells and tissues (ucberkeley page)

hypothetically: continuous eating ie snacking generates a constant stream of insulin

in the circulation, insulin is degraded within minutes in the liver and kidneys

i read: fat cells inhibit the action of insulin = insulin resistance

insulin resistance can cause insulin release at greater concentration/amount
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  • NEUROMANTIC
    Tension and stress lead directly to weight gain. Stress produces the cortisol hormone. Cortisol, besides causing major damage to tissue and nerves when stored up, also signals the production of insulin. Some extra insulin sounds harmless enough, except that it tells your body to store fat in the abdomen, as more and more studies are showing.

    -Mike Kramer, Staff Writer, "The Secret Benefits of Massage: The Easiest Way to Combat Stress & Fight Fat"
    1115 days ago
  • NEUROMANTIC
    When there is a severe deficit of carbohydrates, the body has several immediate reactions, one of which is that it starts using protein as a fuel source. (And fats. edit/) Ketones, a by-product of incomplete fat breakdown, begin to accumulate in the blood

    -Becky Hand, Licensed & Registered Dietitian, "Read This Before Starting a Low-Carb Diet"

    Multiple metabolic pathways are involved in this shift in energy utilization. Hormone sensitive lipase, the activity of which is normally inhibited by insulin, is the main mediator of this process (1–4). This enzyme mediates the degradation of triglycerides and formation of free fatty acids (FFA) (Figure 1) (3).

    The cycle of cellular starvation and ketone formation is further fuelled by increasing concentrations of diabetogenic hormones (glucagon, cortisol, growth hormone, and epinephrine) (1–4). As cellular glucose levels decrease, hepatic glycogenolysis increases (1–5). Glycogenolysis is driven by glucagon with the goal being to increase the glucose available to cells. This mechanism is very rapid and occurs within minutes (4). Glucagon acts on the cellular membrane of hepatocytes activating adenylate cyclase which triggers a series of reactions that result in hyperglycemia (4).

    -Vladimir Stojanovic and Sherri Ihle, "Role of beta-hydroxybutyric acid in diabetic ketoacidosis: A review"
    1116 days ago
  • NEUROMANTIC
    The body converts digestible (non-fiber) carbohydrates into glucose. The glucose then enters the bloodstream. Insulin is secreted from the pancreas, which allows the glucose to enter the body's cells to be used as fuel. Some glucose is stored as glycogen in the liver and muscles for future use, like fueling a long workout. If there is extra glucose, the body will store it as fat.

    The speed at which carbohydrate foods are digested and utilized by the body, as well as the increase in blood sugar level and insulin production, depends on many factors. These factors include the following: the type and amount of carbohydrate eaten, the amount of fiber contained in the food, other foods that are eaten with the meal or snack, physical activity, stress and certain medical conditions

    When there is a severe deficit of carbohydrates, the body has several immediate reactions, one of which is that it starts using protein as a fuel source. (Or fat and) Ketones, a by-product of incomplete fat breakdown, begin to accumulate in the blood. -a little edit/

    -Becky Hand, Licensed & Registered Dietitian "Read This Before Starting a Low-Carb Diet" Becky Hand, August 2017.
    Article created on: 8/31/2017

    1120 days ago
  • DONNALEE-53
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    1163 days ago
  • NEUROMANTIC
    The fat that lies just below your skin in most of your body -- the kind you can grab with your hands -- is called subcutaneous fat. In your belly, it’s called visceral fat because it builds up in the spaces between and around your viscera -- internal organs like your stomach and intestines.

    This visceral fat in your middle makes toxins that affect the way your body works, says Samuel Dagogo-Jack, MD, president of the American Diabetes Association. Among them are chemicals called cytokines that boost your chances of heart disease and make your body less sensitive to insulin, which can bring on diabetes.

    Belly fat is sneaky. Because it’s tucked away inside your body, Dagogo-Jack says, you could have “a false sense of security” about how healthy you actually are. You may not be seriously overweight, but that doesn’t mean you don’t have a problem.

    How can you tell if your belly fat is putting your health at risk? That part is easy. No special blood tests or scans are required. All you need is a tape measure. The size of your waist says it all.

    The higher the number, the greater the danger your tummy poses to your health.

    For women, a waist measurement of 35 inches or more is cause for concern.

    For men, a waist measurement of 40 inches or more could spell trouble. (webmd.com)
    1178 days ago

    Comment edited on: 7/16/2017 9:01:34 AM
  • ICECUB
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    1179 days ago
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