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1CRAZYDOG's Photo 1CRAZYDOG Posts: 618,494
12/18/19 7:28 P

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I can visualize the ad but can't remember for sure. . . was it Crestor?? Not sure.

Love is the root of all things good in life.


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ECOAGE's Photo ECOAGE Posts: 12,955
12/18/19 3:52 P

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I've been on statins for decades. Yup, decades. High cholesterol is not because of my diet!

Barb, do you remember the old tv ad for a statin with food and a relative that looked like that food? I've been trying to remember which statin and I want to find that ad.

It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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1CRAZYDOG's Photo 1CRAZYDOG Posts: 618,494
12/18/19 2:15 P

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I personally do take Ubiquinol. Was on a statin for a year when first diagnosed w/type 2. Wel, I am glad I didn't stay on it any longer! Feel so much better not taking it and when I read the side effects . . . oy.

Love is the root of all things good in life.


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ECOAGE's Photo ECOAGE Posts: 12,955
12/18/19 2:12 P

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Coenzyme Q10

Coenzyme Q10
examine.com/supplements/coenzyme-q10
/

The standard dose for CoQ10 is generally 90mg for a low dose and 200mg for the higher dose, taken once daily with a meal due to its reliance on food for absorption. Dose-dependence is not commonly observed with CoQ10 supplementation and 90mg tends to be the best cost-effective dose.

CoQ10 supplements can be either the oxidized form (ubiquinone) or reduced form (ubiquinol) as both forms seem pretty equally potent in increasing circulating levels of total CoQ10 in the body. Grapefruit juice may increase CoQ10 bioavailability

There generally isn't too much of a therapeutic effect of CoQ10 supplementation (mostly taken with the 'just in case' mentality that pervades multivitamin supplementation), although for people who have previously experience a heart attack or damage to cardiac tissue as well as for people on statin therapy supplementation becomes much more important.

Statins

Statin usage (long-term, not short-term is known to cause lower serum CoQ10 levels and this lower CoQ10 level is an independent predictor of statin-related cardiovascular disease risk while being associated with depression and possible causative of statin-related myopathy.
Prolonged statin usage is causative of reduced circulating CoQ10 levels, and this reduction of CoQ10 below normal levels is thought to mediate a large amount of adverse effects associated with statin treatment. CoQ10 usage alongside statin usage is commonly seen as a way to prevent statin-related myopathy. Ingestion of at least 90-100mg CoQ10 daily alongside statin usage is associated with greatly reduced risk from statin-related pathologies
The combination of CoQ10 and statins seem to work additively in increasing HDL-C.

emoticon Best Bioavailability: Ubiquinol vs. Ubiquinone, Liquid CoQ10
www.superfoodly.com/best-bioavailabi
li
ty-ubiquinol-vs-ubiquinone-liquid-coR>q10/

emoticon Whatís the best CoQ10?
Ubiquinol, which is the reduced form, is better than ubiquinone for bioavailability. While both ubiquinone and ubiquinol supplements are believed to boost CoQ10 levels, given the poor bioavailability that both have, itís easy to grasp why the reduced form is superior for supplementation. It saves your body a step; enzymatic conversion to make it into the usable type isnít needed with ubiquinol.

Kaneka QH is the branded name for ubiquinol sold to various supplement manufacturers for use in their products.

When it comes to variations of ubiquinol and ubiquinone, using different encapsulation and delivery methods, there isnít enough data to adequately compare them.

emoticon Qunol Reviews: Is Ultra CoQ10 Really Better Than Ubiquinol?
www.superfoodly.com/qunol-reviews-is
-u
ltra-coq10-really-better-than-ubiquiR>nol/


emoticon CoQ10 Foods: The 50 Highest Natural Dietary Sources
www.superfoodly.com/coq10-foods-the-
50
-highest-natural-dietary-sources/


_______________________________

emoticon Topical Coenzyme Q10
examine.com/supplements/coenzyme-q10
/


CoQ10 has exhibited increased elasticity potential (increased elastin expression and preservation of collagen, anti-wrinkle effects via protection from UV, and depigmentation potential.

Application of a cream containing 0.01% CoQ10 twice daily.

A few studies have used combination therapy, usually with Vitamin E, retinyl palmitate (highly bioactive form of Vitamin A), grape seed extract (as oil) and linseed oil which has noted UV protection and reduced wrinkling in aged subjects.

It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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1CRAZYDOG's Photo 1CRAZYDOG Posts: 618,494
12/9/19 6:59 P

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Yes, some of the studies that 'substantiate' a finding are really so ill designed or small that the results are not meaningful! It affects the reliability of the results so much.

Love is the root of all things good in life.


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ECOAGE's Photo ECOAGE Posts: 12,955
12/9/19 4:30 P

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My pleasure. I'm trying to figure out what to buy and restock. Everything is "the best" if you go by their ads.

So many informative sites turn out to be there for sales rather than information. I want to cut through the marketing. How many participants were in a study ... four or four hundred? What was used for comparisons? Basically, is a statement based on evidence-based research ... or not?

Supplements, essential oils, and other active ingredients can be powerful supports for health. Or they can be a waste of $$$.

It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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1CRAZYDOG's Photo 1CRAZYDOG Posts: 618,494
12/9/19 3:40 P

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Thanks for the links! Appreciate all the information.

Love is the root of all things good in life.


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ECOAGE's Photo ECOAGE Posts: 12,955
12/9/19 2:01 P

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curcumin, the active ingredient in turmeric

There seems to be good info available. I'm sharing too much good information! This stuff gets confusing!

Look at all the variables and choices without even considering brands. Bioavailability is one factor. With or without pepper is the other factor. But then potency? Enhanced bioavailability and lesser amount of curcumin?

Turmeric for Health (2019 update)
www.turmericforhealth.com/curcumin-b
en
efits-and-dosage/8-popular-curcumin-R>supplement-types-in-market-today-a-q
ui
ck-review


Summary of Curcumin (11/26/2019)
Primary Information, Benefits, Effects, and Important Facts
examine.com/supplements/curcumin/#ho
w-
to-take


Best type of Curcumin? (BioPerine vs Longvida vs Meriva vs Theracurmin vs BCM-95)
(2017)
www.reddit.com/r/Nootropics/comments
/6
d85zc/best_type_of_curcumin_bioperinR>e_vs_longvida_vs/


Which Curcumin Supplement Has The Best Absorption? (2/20/2019)
www.superfoodly.com/best-turmeric-cu
rc
umin-supplement/


It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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1CRAZYDOG's Photo 1CRAZYDOG Posts: 618,494
12/9/19 5:36 A

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Thanks, Gail!

Love is the root of all things good in life.


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ECOAGE's Photo ECOAGE Posts: 12,955
12/9/19 3:12 A

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Black Pepper is a source of piperine. It is ingested alongside some supplements to increase their absorption rates and is frequently included in a blend with curcumin.

Summary of Black Pepper (10/3/2019)
Primary Information, Benefits, Effects, and Important Facts
examine.com/supplements/black-pepper
/


BioPerine Benefits | Itís More Than Just Black Pepper Extract (10/15/2019)
www.dietspotlight.com/bioperine-bene
fi
ts/


It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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ECOAGE's Photo ECOAGE Posts: 12,955
12/9/19 3:04 A

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Examine.com emoticon
Examine.com is the largest database of nutrition and supplement research on the Internet. Founded in early 2011, it is a systematic and objective database, free from advertising or industry partnerships. As an educational organization, they are not affiliated with any supplement or food company.

emoticon List of Supplements
All our supplement pages are backed with references to scientific papers.
examine.com/supplements/

emoticon Nutrition and Supplement Articles
Answers to your questions on nutrition and supplements.
examine.com/nutrition/

Edited by: ECOAGE at: 12/9/2019 (14:00)
It takes a long time to grow young. - P. Picasso

Gail
~~~SparkTeam Leader ~~~
~ Virtual Walk/Run/Cycle Team
~ Four Seasons Challenge
~ Calling All Vegetarians and Vegans


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